Royal jelly is produced by stimulating colonies with movable frame hives to produce queen bees. Royal jelly is collected from each individual queen cell when the larva is about four days old. It is collected from queen cells because these are the only cells in which large amounts are deposited; when royal jelly is fed to worker larvae, it is fed directly to them, and they consume it as it is produced, while the cells of queen larvae are "stocked" with royal jelly much faster than the larva can consume it. Therefore, only in queen cells is the harvest of royal jelly practical.
A well-managed hive during a season of 5-6 months can produce approximately 500g of royal jelly. Since the product is perishable, producers must have immediate access to proper cold storage (e.g., a household refrigerator or freezer) in which the royal jelly is stored until it is sold or conveyed to a collection centre.
This product is combined with honey for preservation, as it spoils easily.
People collect and sell royal jelly as a dietary supplement, claiming various health benefits because of components like B-complex vitamins such as pantothenic acid (vitamin B5) and vitamin B6 (pyridoxine); it can also be found in various beauty products. The overall composition of royal jelly is 67% water, 12.5% crude protein (including small amounts of many different amino acids), and 11% simple sugars, also including a relatively high amount (5%) of fatty acids. It also contains many trace minerals, some enzymes, antibacterial and antibiotic components, and trace amounts of vitamin C[1]. Contrary to claims by many of those promoting its use, vitamins A, D, and E are completely absent from royal jelly [1]. Independent research has already disproved, or is needed to confirm or disprove, many of the purported health claims, such as reports of hormonal activity (unknown in the bees themselves; the most abundant sterol is cholesterol, which is not itself a hormone). To date, there is only preliminary evidence that it may have some cholesterol-lowering effects, as well as immunomodulatory, anti-cancer, anti-inflammatory, wound-healing and antibiotic effects, though the last three of these effects are unlikely to be realized if ingested (digestion of the substances involved, or neutralization via changes in pH).(wikipedia)
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